Dr. Rader is the Cooper-McClure Professor of Medicine and is Professor of Pathology and Pharmacology at the University of Pennsylvania School of Medicine. He is Director of the newly created Clinical and Translational Research Center and Associate Director of Penn’s Institute for Translational Medicine and Therapeutics. He is also the Director of Preventive Cardiovascular Medicine and Lipid Clinic and the Director of the Lipid-Atherosclerosis Research Unit. Dr. Rader’s basic research laboratory focuses on genetic and pharmacologic regulation of lipoprotein metabolism and atherosclerosis, and he directs a translational research program focusing on human genetics of lipid disorders and atherosclerosis and novel approaches to treatment of dyslipidemia and regression of atherosclerosis. He has a particular interest in HDL metabolism, factors and genes involved in its regulation, the causal nature of the relationship of HDL metabolism to atherosclerosis, and novel approaches to targeting HDL metabolism and reverse cholesterol transport in the treatment, prevention, and regression of atherosclerosis.
Dr. Rader received his undergraduate degree from Lehigh University and his medical degree from the Medical College of Pennsylvania. He completed an internship and residency in internal medicine at Yale-New Haven Hospital, followed by a year as a Chief Resident. In 1988 he began a fellowship in lipid metabolism at the Molecular Disease Branch of the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, and was subsequently appointed to a staff scientist position. He was recruited in 1994 to the University of Pennsylvania.
Dr. Rader is a member of the American Society of Clinical Investigation and the Association of Academic Physicians, and a recipient of a Burroughs Wellcome Fund Clinical Scientist Award in Translational Research, a Doris Duke Charitable Foundation Distinguished Clinical Scientist Award, and a Bristol Myers Squibb "Freedom to Discover" Unrestricted Cardiovascular Research Grant. Dr. Rader is an Associate Editor of the Journal of Clinical Investigation and an editorial board member of Arteriosclerosis Thrombosis and Vascular Biology, American Journal of Physiology (Endocrinology and Metabolism), Circulation, Circulation Research, Journal of Lipid Research, and Trends in Molecular Medicine. Dr. Rader has authored over 250 peer-reviewed publications, review articles, and book chapters, including chapters on lipoprotein disorders for Harrison’s Principles of Internal Medicine, Topol’s Textbook of Cardiovascular Medicine, and Nelson’s Textbook of Pediatrics. He is a frequently invited speaker nationally and internationally on his basic and translational research in lipoprotein metabolism and atherosclerosis. |
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