2014 CME Symposia - Breakfast Symposium B

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Pre-registration for symposia will open at the end of August for CMHC registrants to make selections. There are no additional fees to attend. Symposia include meals or refreshments and seating is limited and on a first-come, first-serve basis.

Breakfast Symposium B

Friday · 6:15 - 7:45am

Innovations in GLP-1 Receptor Agonist Therapy:
Individualized Treatment Strategies to Overcome Barriers and Reduce Cardiometabolic Risk in Type 2 Diabetes Mellitus

Supported by an educational grant from Lilly USA, LLC

Symposium Overview

Some of the newer type 2 diabetes therapies, including GLP-1 receptor agonists, do not carry the same limitations as traditional therapies. This class of drugs has been shown to improve global cardiometabolic risk factors and to improve the function of beta cells, rather than just address hyperglycemia. Our faculty will help clinicians understand the differences between GLP-1 receptor agonists, not only in terms of their mechanisms of action, but in terms of their impact on glucose control, beta cell function, and cardiovascular risk factors such as body weight, blood pressure, and lipid profiles. A review of current guideline recommendations will help clinicians appropriately integrate this class of medications into clinical practice to improve outcomes in the management of type 2 diabetes.

Learning Objectives

  • Overcome common barriers to patient acceptance of and adherence to T2DM therapies by individualizing treatment strategies, minimizing adverse events and side effects, and increasing patient satisfaction.
  • Discuss the physical structure and pharmacokinetic/pharmacodynamic data for available and emerging short-acting and long-acting GLP-1 receptor agonist therapies and discuss how each agent differs in terms of its effects on HbA1c, fasting and post-prandial glucose, non-glycemic parameters, and safety/tolerability.
  • Cite the effects of GLP-1 receptor agonists on cardiovascular risk factors such as body weight, blood pressure, and lipid profiles.
  • Identify patients most likely to benefit from GLP-1 receptor agonist therapy, based on patient characteristics such as comorbidities, co-medications, and attitudes toward injections, and individualized guideline-based treatment regimens.

Preliminary Agenda & Faculty

6:15 - 6:20am Opening Remarks Chairperson: John B. Buse, MD, PhD
6:20 - 6:35am Clinical Practice Guidelines for Managing Patients with Type 2 Diabetes: Where do Incretins Fit into the Treatment Paradigm? Presenter: John B. Buse, MD, PhD
6:35 - 7:00am GLP-1 Receptor Agonists: Similarities and Differences Presenter: Richard E. Pratley, MD
7:00 - 7:20am The Role of GLP-1 Receptor Agonists in Overcoming Common Patient Treatment Barriers Presenter: Samuel Dagogo-Jack, MD
7:20- 7:45am Improving and Addressing Cardiometabolic Risk with GLP-1 Receptor Agonists Moderator: John B. Buse, MD, PhD
Presenters & discussants: Samuel Dagogo-Jack, MD; Richard E. Pratley, MD

John B. Buse, MD, PhD

  • Verne S. Caviness Distinguished Professor
  • Chief, Division of Endocrinology
  • Director, Diabetes Care Center
  • Executive Associate Dean for Clinical Research
  • University of North Carolina School of Medicine
  • Chapel Hill, NC

Richard E. Pratley, MD

  • Director, Florida Hospital Diabetes Institute
  • Senior Scientist, Translational Research Institute
    for Metabolism and Diabetes
  • Professor, Sanford Burnham Medical Research Institute
  • Winter Park, FL

Samuel Dagogo-Jack, MD

  • Professor of Medicine
  • Director, Div. of Endocrinology, Diabetes & Metabolism
  • A. C. Mullins Chair in Translational Research
  • Director, General Clinical Research Center
  • Director, Endocrinology Fellowship Training Program
  • University of Tennessee Health Science Center
  • Memphis, TN

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