Dr. Simon is Chief, Division of Cardiovascular Medicine and Director, Harrington Heart & Vascular Institute, University Hospitals Case Medical Center; Director, Case Cardiovascular Center and Herman K. Hellerstein Professor of Cardiovascular Research and Professor of Medicine, Case Western Reserve University School of Medicine. He graduated summa cum laude from Harvard College. After earning his medical degree from Harvard Medical School, he completed his internal medicine residency and cardiovascular medicine fellowship at Brigham and Women's Hospital and interventional cardiology training at Beth Israel Hospital, Boston. He joined the faculty of Brigham and Women's Hospital where he rose through the ranks to Associate Director, Interventional Cardiology, Brigham and Women's Hospital, and Associate Professor of Medicine, Harvard Medical School.
A recipient of numerous research awards, Dr Simon was elected into the American Society for Clinical Investigation, Association of University Cardiologists, and the Association of American Physicians. He is a recipient of the prestigious MERIT Award from the National Heart, Lung, and Blood Institute. He is also a Fellow of the American College of Cardiology, the American Heart Association, and the Society of Cardiac Angiography and Interventions. Dr Simon's main area of research interest is the role of inflammation in vascular injury and repair. His research is supported by grants from the National Institutes of Health. Using cutting edge transcriptional profiling approaches, his laboratory has identified a novel biomarker called MRP-8/14 that predicts the risk of future heart attack and stroke. As Director of the Ohio Cell-based Therapy Consortium-Cardiovascular, Dr Simon is committed to advancing stem cell and regenerative medicine efforts to treat advanced heart and vascular disease. He is an active interventional cardiologist and continues to play a leading role in national and international clinical trials investigating new devices and anti-thrombotic drugs. Dr Simon has been recognized in Best Doctor's in America and US News Top Doctors. He has published extensively in peer-reviewed basic science and clinical journals. Dr Simon also serves on the Editorial Boards of Circulation and Journal American College Cardiology, and recently completed a stint as Associate Editor for Circulation where he continues to serves as Guest Editor.