Biography: Paul M. Ridker, MD, MPH

Paul M. Ridker, MD, MPH
  • Eugene Braunwald Professor of Medicine
  • Harvard Medical School
  • Director
  • Center for Cardiovascular Disease Prevention
  • Brigham and Women's Hospital
  • Boston, MA

Dr. Ridker is the Eugene Braunwald Professor of Medicine at the Harvard Medical School and directs the Center for Cardiovascular Disease Prevention, a translational research unit at the Brigham and Women's Hospital in Boston which focuses on the molecular and genetic epidemiology of cardiovascular diseases and on novel strategies for cardiovascular disease detection and prevention.

As a graduate of Brown University, the Harvard Medical School, and the Harvard School of Public Health, Dr. Ridker's primary research brings together classical tools of large-scale, population based epidemiology with emerging genetic and molecular techniques designed to improve our ability to predict and prevent vascular disease. Particular areas of interest involve molecular and genetic determinants of hemostasis, thrombosis, and inflammation with a focus on "predictive medicine", early disease diagnosis, and the underlying causes and prevention of acute coronary syndromes. Dr. Ridker's research efforts are primarily supported by RO1 research grants from the National Heart, Lung, and Blood Institute (NHLBI), a Distinguished Clinical Scientist Award from the Doris Duke Charitable Foundation, and through philanthropic research grants from the Leducq Foundation and the Donald W Reynolds Foundation. Dr. Ridker additionally directs an NHLBI-funded institutional National Research Service Award (training grant) in cardiovascular epidemiology at the Brigham and Women's Hospital and Harvard Medical School. Dr. Ridker has been the recipient of both a Clinician Scientist Award (1992-1997) and an Established Investigator Award (1997-2002) from the American Heart Association. A frequent invited lecturer at national and international conferences, Dr. Ridker lists among his honors elected membership into the American Society for Clinical Investigation (ASCI), the American Epidemiological Society (AES), and the American Association of Physicians (AAP). Citing his pioneering work on inflammation, CRP, and atherothrombosis, Time Magazine honored Dr. Ridker as one of America's Ten Best Researchers in Science and Medicine in 2001 and as one of the "Time 100" in 2004. Dr Ridker currently serves on the Board of External Experts for the National Heart Lung and Blood Institute. In addition to his work in cardiovascular epidemiology, Dr Ridker has been the Principal Investigator or Study Chairman of several multinational clinical trials including PREVENT, PRINCE, Val-MARC, LANCET, and the ongoing JUPITER trial evaluating the use of statin therapy among 18,000 apparently healthy individuals with low levels of LDL-C and elevated levels of CRP. Dr Ridker is also the Principal Investigator of the Women's Genome Health Study (WGHS), a comprehensive prospective genome wide association study being conducted among more than 25,000 initially healthy American women.

Dr. Ridker is the author of over 430 original reports, 140 reviews and book chapters, and 5 textbooks related to cardiovascular medicine. A member of multiple editorial boards, Dr. Ridker is a co-inventor on patents filed by the Brigham and Women's Hospital that relate to the use of inflammatory biomarkers in cardiovascular disease.

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