Dr. Lee M. Kaplan is director of the Obesity, Metabolism & Nutrition Institute and founding director of the Weight Center at Massachusetts General Hospital, and is associate professor of medicine at Harvard Medical School. Dr. Kaplan’s clinical expertise is in obesity medicine, gastroenterology and liver disease. The author of more than 150 medical and scientific papers, he has a special interest in the causes and complications of obesity and the development of new and more effective preventive strategies and therapies for this disease. His clinical research is focused on identifying clinically relevant subtypes of obesity, identifying predictors of outcome of obesity therapies, and exploring novel, combination therapies for obesity and its complications. His basic research is focused on the physiological and molecular mechanisms of gastrointestinal regulation of body weight and metabolic function, and his group has pioneered the development and use of rodent models of weight loss surgery and gastrointestinal devices to explore these mechanisms.