FDA Extends Approval for Alirocumab to Lower LDL-C in Pediatric Patients with HeFH 

Addressing an Unmet Need in Pediatric Patients with HeFH  Heterozygous familial hypercholesterolemia (HeFH) affects about 1 in 313 people—characterized by dangerously high low-density lipoprotein cholesterol (LDL-C) levels. Untreated, it can trigger early heart disease. Detecting and treating it early in pediatric patients can prevent heart problems later. American College of Cardiology/American Heart Association guidelines define acceptable LDL-C […]

FDA Expands Labels for Bempedoic Acid Tablets and Combination Bempedoic Acid and Ezetimibe Tablets to Reduce Cardiovascular Risk 

Introduction: Addressing the Need for Improved LDL Management in the US  There is a clear need for innovative treatments to combat cardiovascular disease (CVD).  Heart disease remains the leading cause of death for men and women. 80% of heart attacks and strokes linked to CVD are preventable with optimal risk factor management. However, every 40 seconds, an individual […]

The Role of Meditation in Heart Health

Certain lifestyle and pharmacological interventions have proven effective at lowering the prevalence of CVD risk factors, which has increased apace with worsening population health.  Although, there is a pressing need for novel, cost-effective interventions for primary and secondary prevention as the burden of cardiovascular disease remains steady. Experts continue to report positive data on the […]

Aortic Stenosis: Updated Guidelines for Diagnosis and Management

By Kate Buron In December 2020 the Joint Committee on Clinical Practice Guidelines, a combined effort from the American College of Cardiology (ACC) and the American Heart Association (AHA), released their updated guidelines for the management of patients with valvular heart disease (VHD). Within the new guidelines, the ACC and AHA provide clarity on the […]

Pregnancy-Related Cardiovascular Risk Tied to BMI and Blood Pressure

Women who have experienced hypertensive disorders of pregnancy (HDP) face a doubled risk of cardiovascular disease compared with those who have had normotensive pregnancies – and their risk factor levels remain higher through age 50 and beyond. Hypertensive disorders of pregnancy and cardiovascular disease share a host of common modifiable risk factors including adiposity, hypertension, […]

Association of Cigarette and E-Cigarette Use with CVD Biomarkers 

Although the prevalence of cigarette smoking has significantly declined from nearly 21% of the U.S. adult population identifying as smokers in 2005 to only 14% today, an estimated 34.1 million adults still currently smoke cigarettes. In addition, many have transitioned to the use of electronic cigarettes in hopes of reducing cardiometabolic risks. However, the cardiovascular […]


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