The Influence of Gut Bacteria on Diabetes Drugs

Newly emerging research seeks to investigate the effect of gut microbiota on the efficacy of type 2 diabetes drugs, suggesting that the composition of gut bacteria may illuminate why certain diabetes medications work for some peopleโ€”and not others. Estimates indicate that over 415 million people across the globe have type 2 diabetes, a statistic leading […]

Why Stress May Raise Type 2 Diabetes Risk in Women

Traditional risk factors like obesity, high blood pressure, and a sedentary & nonactive lifestyle may not be the sole risk factors that can predict type 2 diabetes, as newly emerging research highlights the critical role that stress may play in the development of the condition: specifically in women. The study, which will be presented on […]

SGLT-2 inhibitors Associated with Decreased HF Hospitalizations in Type 2 Diabetes

The management of patients with type 2 diabetes (T2D) and heart failure (HF) is challenging, and the optimal care for these patients is not very well defined. The coexistence of these two conditions increases morbidity and mortality. Patients with HF and T2D are at an increased risk for cardiovascular-related mortality and have higher rates of […]

Obesity Yields Spike in Nonalcoholic Fatty Liver Disease

At the recent annual meeting of the American College of Physicians, it was declared that nonalcoholic fatty liver disease (NAFLD) is the 21st century epidemic in liver diseaseโ€”given the extraordinary growth in the disease’s prevalence, due to the related epidemics of both obesity and type 2 diabetes mellitus. Statistics indicate that the global prevalence of […]

Finding Common Ground for Glycated Haemoglobin Test Targets

JoAnn Lindenfeld, MD

In March of this year, the American College of Physicians (ACP) issued a guidance statement on HbA1c targets for adults with type 2 diabetes (T2D), which have been the subject of debates and discussions in the medical community. At the center of this debate is ACPโ€™s recommendation for a target HbA1c goal between 7-8% to […]

Inflammation and risk of T2DM: Insights from the CANTOS trial

Data from several studies have suggested that persistent low-grade inflammation has an important role in the pathophysiology of many cardiometabolic conditions. Inflammatory markers, such as interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hs-CRP) have been associated with increased risk of cardiovascular adverse events, as well as insulin resistance and hyperglycemia. Canakinumab is a human monoclonal antibody […]

The Co-Occurrence of Diabetes & Heart Disease

The number of people living with diabetes has tripled since 2000, leading to enormous financial ramifications: the global cost of the disease is $850 billion each year. The latest estimates from the International Diabetes Federation indicate that one in 11 adults worldwide have diabetes; most have type 2 diabetes, which is strongly linked to obesity […]

Moderate Drinking May Help Prevent Diabetes

A study published in Diabetologia, conducted by researchers from the National Institute of Public Health of the University of Southern Denmark, suggests that people who drink three to four times a week are less likely to develop type 2 diabetes than those who never drink. The study, which surveyed over 70,000 people on alcohol intake, […]

Biomarkers Could Predict Best Diets

A new study, published in the American Journal of Clinical Nutrition, has indicated two biomarkers that can predict the efficacy of certain diets for weight loss: specifically, for people with prediabetes or diabetes. Through an analysis of over 1,200 adults, researchers discovered that a personโ€™s fasting blood glucose levels, fasting insulin levels, or both, could […]

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