Dyslipidemia is the imbalance of lipids such as cholesterol, low-density lipoprotein cholesterol, (LDL-C), triglycerides, and high-density lipoprotein (HDL), resulting from diet, tobacco and alcohol use, sedentary lifestyle, or genetic factors such as familial hypercholesterolemia. It is a leading cause of cardiovascular disease and may contribute to severe complications.

CME Activities

News Digest

Expert Highlights and Perspectives

Recap of Major Lipid-Lowering Trials at 2023 ACC

FACULTY SPOTLIGHT
Christie M. Ballantyne, MD
Christie Ballantyne, MD
Erin D. Michos, MD, MHS
Erin Michos, MD

Watch Dr. Ballantyne and Dr. Michos discuss key trials in lipid lowering presented at 2023 ACC, including CLEAR Outcomes with bempedoic acid, a phase 2 trial with oral PCSK9 inhibitor MK-0616, as well as their potential implications. Recorded March 10, 2023

Lipid Management in the Post-ACS Patient

FACULTY SPOTLIGHT
Christie M. Ballantyne, MD
Christie Ballantyne,
MD
Erin D. Michos, MD, MHS
Erin Michos,
MD
Salim S. Virani,
MD

Watch Drs. Ballantyne, Taub, and Virani discuss some practical pearls about the optimization of lipid-lowering therapy in patients with a recent MI or an acute coronary syndrome (ACS) event. They discuss suboptimal LDL-C levels in these patients, reasons for these gaps, and how to lower LDL-C levels early and effectively with evidence-based therapies in order to minimize the risk of recurrent events. (Recorded June 20, 2022). 

Expert Perspectives and Recent Developments in LDL-C Lowering

FACULTY SPOTLIGHT
Christie M. Ballantyne, MD
Christie Ballantyne,
MD
Erin D. Michos, MD, MHS
Erin Michos,
MD
Joseph Saseen, PharmD
Joseph Saseen,PharmD

Watch Drs. Ballantyne, Michos, and Saseen discuss some practical pearls about recent developments in LDL-C lowering. They discussed combination therapy and constantly evolving lipid therapy, including data about monoclonals, and siRNA, also presented at 2022 AHA meeting. Recorded on Dec. 14, 2022.

CMHC Annual 2021 Lipid Management Panel

FACULTY SPOTLIGHT
Robert Eckel,
MD
Christie M. Ballantyne, MD
Christie Ballantyne,
MD
Matthew J. Budoff, MD
Matthew Budoff,
MD

CMHC Chairs Christie Ballantyne, MD and Robert Eckel, MD, as well as CMHC faculty Matthew Budoff, MD recap the lipid sessions presented at the 16th Annual CMHC, including perspectives and clinical pearls on ASCVD risk assessment, residual ASCVD risk, and ASCVD management and prevention.

Lipid Management in Very High-Risk Patients Post-MI: Expert Perspectives with Drs. Taub, Desai, Shapiro

FACULTY SPOTLIGHT
Pam Taub, MD
Pam Taub,
MD, FACC
Nihar R. Desai,
MD, MPH, FACC
Michael D. Shapiro,
DO, MCR, FACC, FAHA

Watch Drs. Taub, Desai, and Shapiro discuss some additional perspectives on the management of very high-risk, including:

  • The safety of very low LDL-C
  • Concerns with statins and new-onset diabetes and how to address overall patient concerns about lipid-lowering therapy
  • Residual ASCVD risk beyond LDL-C

Drug Pipeline

LDL-C Lowering

Lp(a) lowering

Triglyceride lowering

ASCVD = atherosclerotic cardiovascular disease; | HTG = hypertriglyceridemia; | siRNA = small interfering RNA | ASCVD = atherosclerotic cardiovascular disease; | CVD = cardiovascular disease | HeFH = heterozygous familial hypercholesterolemia | HoFH = homozygous familial hypercholesterolemia | HTG = hypertriglyceridemia | Lp(a) = lipoprotein (a); | PCSK9 = Proprotein convertase subtilisin/kexin type 9 interfering RNA | siRNA = small;

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